Objective: To construct the Price Index of Primary Medical Service (PIPMS) by using the price basket tool and weight- ed price index, and to explore the application prospect of the index to explain the price level and regional comparison of the combina- tion of primary medical services in a certain region. Methods: Literature analysis, price index, statistical analysis are applied. Re- sults: (1) The price basket is the key parameter for constructing the PIPMS index, which is a series of items and frequency combina- tions guided by a certain policy goal, which can establish a comprehensive price basket and a characteristic price basket (high market share, key monitoring and value points). (2) The price comparison relationship of medical service items with different value points is unreasonable, especially in the central and western regions. (3) The internal influence degrees of the PIPMS index value in each province were medical technology, clinical, comprehensive and traditional Chinese medicine. No external factors affecting the PIPMS index have been identified in the provinces, indicating that macro-control is less effective. Discussion: (1) The PIPMS index tool reflects the decision-making management ideas of medical insurance big data. (2) The PIPMS index helps to realize the price macro-control mechanism. (3) PIPMS helps in price monitoring of medical services.